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Vol.44, 2025 YAFO Weekly Global Wrap-up Report 雅法全球生物医药交易周报

2025-02-24

1. Summary of the week

From February 15 to 21, a total of 12 deals were signed globally. In China’s biotech industry, there were 3 out-licensing deals, 1 in-licensing deal, and 2 domestic deals.

The top out-licensing deal of the week was between Behai Biotech and Zydus Lifesciences for BH009 (docetaxel), a Phase III asset, with an upfront payment of $27.8 million. Meanwhile, AstraZeneca acquired FibroGen China including the asset Roxadustat, an approved small molecule.

Globally, 6 deals were finalized. The most significant was the licensing and option agreement between Stoke Therapeutics and Biogen for Zorevunersen, an ASO product targeting SCN1A, with an upfront payment of $165 million and a total deal value of $550 million.

2025年2月15日-21日,全球医药市场共签署了12项资产授权和合作协议。中国市场共达成6项交易,包括3项出海交易、1项引进交易和2项国内交易。

本周最大的出海交易是贝海生物授予 Zydus Lifesciences临床三期资产BH009(多西他赛改良型新药)在美国市场的独家商业化权益,首付款2780万美元。阿斯利康以1.6亿美元收购珐博进中国,并获得已上市药物罗沙司他在中国的所有权利。

国际市场上,本周共签署了6项资产授权和合作协议。最大的一笔交易是Biogen引进Stoke Therapetutics一款针对SCN1A基因的ASO药物Zorevunersen,首付款1.65亿美元,总价值5.5亿美元。

2. Licensing Deals

2a. China section

2b. Global section

3. M&A Deals

4. Top Deals of 2024

5. 2019-2024 China Innovative Drug Licensing Transactions

About YAFO CAPITAL

Founded in 2013, YAFO Capital is a Shanghai-based boutique investment and advisory firm, with a professional team in our China, U.S., EU, and SEA offices. Partnering with Pharmaceutical companies, YAFO Fund mainly invests in global assets. YAFO Life Sciences is a leading advisory boutique focused on asset transactions. YAFO has built a strong proven track record and closed dozens of in-licensing and out-licensing transactions with global pharma and biotech companies. Over the past five years, YAFO has been ranked as the No. 1 advisor for China cross-border licensing transactions.  For more information, please visit http://www.yafocapital.com
雅法资本成立于2013年,作为新型投资和投行咨询机构,致力于中国及海外生物医药项目的投融资、资产跨境交易和资产孵化等。旗下雅法基金联合药企进行资产投资和并购,雅法全球医疗专注于医药产品跨境及国内授权交易。基于雅法在全球广泛的人脉与资源网络,在过去十年成功推进了大量的海外项目进入中国市场并协助多个中国产品完成海外授权。雅法拥有经验丰富的全球交易团队,覆盖美国、日本 、欧洲等全球主要医药创新区域。核心合伙人均为华尔街资深投行人士或具有跨国药企经历,为客户交易提供强力支持。雅法总部位于上海,在美国、欧洲、东南亚等地均设有分部。雅法在生物医药跨境授权及并购业务交易数量连续多年排名第一。

Event Name
2025-06 ACCESS CHINA @ Boston ForumVirtual & Boston